The following images give an idea of the types of analyses that
can be performed using our MicroCT instrument. Click on any of the
images for a larger view.
The structure of biological scaffolds can be imaged in three
dimensions. Properties such as volume and porosity can also be
calculated. (Prof. W. Sun)
MicroCT has many applications in the biomedical field one of
which is the characterization of bone growth. The figure shows the
use of microCT to quantify the orientation of vascular spacing in
the bone cortex. The radially oriented vessels grow beneath
endosteal (blue arrow) and periosteal (yellow arrow)
surfaces.(Prof. H. Goldman)
Imaging the skeletal structure of small animals is possible with
Agglomerated soil. Three phases are visible, air, water, and
grains. (Prof. D. Gimenez, Rutgers University)
The effects of degrading bacteria on pure phase
trichloroethylene from cleaning solvents will show whether
bioremediation is plausible for treating contaminated soil. As seen
in the figure, microCT is a suitable technique for determining a
mass transfer rate coefficient for the dissolution of TCE in the
presence of a ganglion from 0 (a) to 17 (b) hours. (Prof. M.
A void within a structure can be highlighted such as the open
space left behind when a corkscrew is removed from a piece of cork.
Three dimensional fracture analysis can be done with no sample
The cross section of sugar beads before (Left) and after (Right)
being compressed can be used to understand the fragmentation
mechanisms in similar systems.
Fabricators of micro-integrated circuits can use tomography to
characterize internal defects.
Visualization of an internal fracture is imaged with no sample
preparation. The cross section is a cracked plastic button from a
Fractured briquette after exiting from rolls.
MicroCT can be used to determine the quality of thin coatings.
The Figure shows a nano-particulate calcium carbonate coating on
the right side of the .5 mm thick paper samples. The CaCO3 has a
high X-radiation absorption level which creates a halo effect as
seen in the zoomed in image.
The X-radiation absorption levels of two different components of
a composite system can be binarized, colored, and 3-D modeled to
define structure. The dispersion of silica in a Nylon matrix for
thermal plasma coating of metal substrates is seen in the figure.
Comparing this to the porosity shows that the silica concentrates
at splat boundaries. (Prof. R. Knight)
Identification of the active ingredient in pharmaceutical
tablets can be done without sample destruction or preparation. High
atomic number active ingredient can be readily identified within a
Through the reconstruction of pharmaceutical tablet cross
sections, internal phase distribution can be viewed without any
sample destruction or preparation. This is important for the
processing and performance of the tablet because each component has
different chemical and mechanical properties.
With the aid of a mechanical testing stage, diametrical
compression tests can be interrupted at any load and the specimen
can be scanned to obtain full three dimensional analysis of
Interrupted dissolution study of a control release tablet.